Influenza A virus subtype H1N1, also known as A(H1N1), is a subtype of influenzavirus A and the most common cause of influenza (flu) in humans.
Influenza A virus strains are categorized according to two proteins found on the surface of the virus: hemagglutinin (H) and neuraminidase (N). All influenza A viruses contain hemagglutinin and neuraminidase, but the structure of these proteins differs from strain to strain due to rapid genetic mutation in the viral genome.
Influenza A virus strains are assigned an H number and an N number based on which forms of these two proteins the strain contains. There are 16 H and 9 N subtypes known in birds, but only H 1, 2 and 3, and N 1 and 2 are commonly found in humans.
Current reports on Swine Flu outbreak and how it was detected.
The 2009 swine flu outbreak is the epidemic of a new strain of influenza virus that was clinically identified in April 2009. The new virus strain is a type of influenza A (H1N1) virus, commonly called the swine flu. It is currently a phase 5 outbreak, one level below an official pandemic.
The time and location of the outbreak is still unknown, but it was first detected in two cases in Southern California in late March. When this novel virus was publicized, officials in Mexico suspected a link to an outbreak of late-season flu cases they were finding. Within days, hundreds more suspected cases were discovered in Mexico, with more cases also showing up in the U.S. and several other countries. By late April, officials from the U.N.'s World Health Organization (WHO), based in Switzerland, and the Centers for Disease Control and Prevention (CDC) in the U.S., were expressing serious concern about the flu outbreak, worried that it might become a worldwide flu pandemic.
By April 28, the new strain was confirmed to have spread to Spain, the United Kingdom, New Zealand, and Israel, and the virus was suspected in many other nations. As a result, WHO raised its alert level to "Phase 5" out of 6 possible, which it defines as a "signal that a pandemic is imminent". By the end of April, 300 schools had closed across the United States and the Mexican government ordered a multi-day shutdown of all non-essential activities in the government and private sector, amounting to a shutdown of most of the country's economy.At the same time, however, many scientists were reaching a consensus that the epidemic was so far "relatively mild," and believed that it could be less fatal than previous pandemics.
The new strain is an apparent reassortment of four strains of influenza A virus subtype H1N1.[53] Analysis by the CDC identified the four component strains as one endemic in humans, one endemic in birds, and two endemic in pigs (swine).However, other scientists have stated that analyses of the 2009 swine flu (A/H1N1) viral genome "suggests that all segments are of swine origin", "[w]e are puzzled about sources of information that affirm that the virus is a reassortment of avian, human and swine viruses," and "this preliminary analysis suggests at least two swine ancestors to the current H1N1, one of them related to the triple reassortant viruses isolated in North America in 1998." One swine strain was widespread in the United States, the other in Eurasia. Worldwide the common human H1N1 influenza virus affects millions of people every year, according to WHO officials, and "these annual epidemics result in about three to five million cases of severe illness, and about 250,000 to 500,000 deaths" annually.In industrialized countries most of these annual deaths occur in people aged 65 or older. By May 2, some pigs in Canada were diagnosed with H1N1. Although some influenza strains can spread between species, the influenza virus is killed by normal cooking procedures, so there is no risk of infection from consumption of well-cooked pork and pork products.
8 years ago

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